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Modulating the thermoresponsive characteristics of PLGA-PEG-PLGA hydrogels via manipulation of PLGA monomer sequences

SeongHoon Jo, Soonjong Roh, Jaemin Shim, Ji Woong Yu, Youngmee Jung, Woo Young Jang, Bumjoon Seo*, You-Yeon Won*, Jin Yoo*

BiomacromoleculesVol. 25, No. 8, pp. 5374-5386(2024)DOI
Hydrogel

Abstract

The thermoresponsive characteristics of PLGA-PEG-PLGA hydrogels are modulated by manipulating PLGA monomer sequences. Sequence-level control of copolymer composition tunes sol-gel transition temperatures and mechanical properties.